Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12614
rs12614
CFB ; CYP21A2
T 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015
dbSNP: rs1883832
rs1883832
CD40
T 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015
dbSNP: rs378352
rs378352
HLA-DOA
T 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015
dbSNP: rs61886277
rs61886277
PLCE1
T 0.700 GeneticVariation GWASCAT Genome-wide Association Study Identifies Genetic Variants Associated With Early and Sustained Response to (Pegylated) Interferon in Chronic Hepatitis B Patients: The GIANT-B Study. 30715261

2019
dbSNP: rs7756516
rs7756516
HLA-DQB2
T 0.700 GeneticVariation GWASCAT A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese. 24940741

2014
dbSNP: rs9276370
rs9276370
HLA-DQA2
T 0.700 GeneticVariation GWASCAT A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese. 24940741

2014
dbSNP: rs9366816
rs9366816
HLA-DPA3 ; LOC105375021
T 0.700 GeneticVariation GWASCAT A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese. 24940741

2014
dbSNP: rs9277535
rs9277535
HLA-DPB1
G 0.760 GeneticVariation GWASCAT A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese. 24940741

2014
dbSNP: rs7453920
rs7453920
HLA-DQB2
G 0.720 GeneticVariation GWASCAT A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese. 24940741

2014
dbSNP: rs1419881
rs1419881
TCF19
G 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015
dbSNP: rs422951
rs422951
NOTCH4
G 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015
dbSNP: rs652888
rs652888
CYP21A2 ; EHMT2 ; EHMT2-AS1 ; LOC107986588
G 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015
dbSNP: rs2856718
rs2856718 		C 0.730 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015
dbSNP: rs78900671
rs78900671
COL22A1
C 0.700 GeneticVariation GWASCAT Genome-wide Association Study Identifies Genetic Variants Associated With Early and Sustained Response to (Pegylated) Interferon in Chronic Hepatitis B Patients: The GIANT-B Study. 30715261

2019
dbSNP: rs9366816
rs9366816
HLA-DPA3 ; LOC105375021
C 0.700 GeneticVariation GWASCAT A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese. 24940741

2014
dbSNP: rs3077
rs3077
HLA-DPA1
A 0.760 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015
dbSNP: rs9277535
rs9277535
HLA-DPB1
A 0.760 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015
dbSNP: rs7453920
rs7453920
HLA-DQB2
A 0.720 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015
dbSNP: rs2853953
rs2853953 		A 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015
dbSNP: rs3130542
rs3130542 		A 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015
dbSNP: rs3077
rs3077
HLA-DPA1
0.760 GeneticVariation GWASCAT A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 23760081

2013
dbSNP: rs3077
rs3077
HLA-DPA1
0.760 GeneticVariation BEFREE Single nucleotide polymorphisms (SNPs) in HLA-DP (rs9277535 and rs3077) and HLA-DQ (rs2856718 and rs7453920) have been repeatedly associated with chronic hepatitis B and spontaneous HBV clearance. 28882445

2017
dbSNP: rs3077
rs3077
HLA-DPA1
0.760 GeneticVariation BEFREE A genome-wide association study identified single nucleotide polymorphisms (SNPs) rs3077 and rs9277535 located in the 3' untranslated regions of human leukocyte antigen (HLA) class II genes HLA-DPA1 and HLA-DPB1, respectively, as the independent variants most strongly associated with chronic hepatitis B. 21346778

2011
dbSNP: rs3077
rs3077
HLA-DPA1
0.760 GeneticVariation BEFREE We also found that the HLA-DPA1 and HLA-DPB1 genes were significantly associated with protective effects against chronic hepatitis B (CHB) in Japanese, Korean and other Asian populations, including Chinese and Thai individuals (P(meta) = 4.40×10⁻¹⁹ for rs3077 and P(meta) = 1.28×10⁻¹⁵ for rs9277542). 22737229

2012
dbSNP: rs3077
rs3077
HLA-DPA1
0.760 GeneticVariation BEFREE Of these variants, SNPs rs3077 and rs9277535 in HLA-DP on chromosome 6 show the strongest evidence for association with CHBVI and with viral clearance. 24846544

2014